APC-957
Retrorsine

Cat. No.

APC-957

CAS No.

480-54-6

MF

C18H25NO6

MW

351.4

Retrorsine is a naturally occurring toxic pyrrolizidine alkaloid.
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Description
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References
Product Name
Retrorsine
CAS No.
480-54-6
MF
C18H25NO6
MW
351.4
Specification
98%
Research Area
Anti-proliferative (hepatocyte), hepatocellular injury research
Description
Retrorsine is a naturally occurring toxic pyrrolizidine alkaloid.
Packing: 10mg, 20mg, 50mg, 100mg, 500mg, 1g, 5g, 10g
Availability: In stock
Storage and Shipping
Store under frozen or refrigerated conditions, keep away from strong light and heat
References
[1]. F J Cubero, et al. Hepatic proliferation in Gunn rats transplanted with hepatocytes: effect of retrorsine and tri-iodothyronine. Cell Prolif. 2005 Jun;38(3):137-46. [2]. S Laconi, et al. Liver regeneration in response to partial hepatectomy in rats treated with retrorsine: a kinetic study. J Hepatol. 1999 Dec;31(6):1069-74. [3]. Yao Lu, et al. Establishment of a novel CYP3A4-transduced human hepatic sinusoidal endothelial cell model and its application in screening hepatotoxicity of pyrrolizidine alkaloids. J Environ Sci Health C Toxicol Carcinog. 2020;38(2):169-185. [4]. Christian Picard, et al. Retrorsine: a kinetic study of its influence on rat liver regeneration in the portal branch ligation model. J Hepatol. 2003 Jul;39(1):99-105.
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
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